Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761931 | 0.95 | MMP2 (0.47) | MMP2MMP9MMP7MMP13SMN1; SMN2 | |
| SCHEMBL8013143 | 0.87 | CCR1 (0.54) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL22761975 | 0.84 | PGR (0.47) | MMP2MMP9MMP7MMP13SMN1; SMN2 | |
| SCHEMBL22761976 | 0.84 | ALDH1A1 (0.47) | MMP2MMP9MMP7MMP13SMN1; SMN2 | |
| SCHEMBL23816714 | 0.81 | ALDH1A1 (0.47) | MMP2MMP9MMP7MMP13SMN1; SMN2 | |
| SCHEMBL8738919 | 0.80 | ALDH1A1 (0.64) | MMP2MMP9SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL22761930 | 0.79 | PGR (0.49) | MMP2MMP9MMP7MMP13NPC1 | |
| SCHEMBL22761977 | 0.77 | NPC1 (0.49) | MMP13SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8221606 | 0.76 | CCR1 (0.56) | MMP13SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23816716 | 0.75 | HDAC3 (0.44) | MMP2MMP9MMP7MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284691-A1 | CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2021-09-16 | — | — | US | disclosed |
| US-20200385424-A1 | CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385424-A1 | CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF | CBX8, CBX3, CBX2 | MMP2 4265/4885MMP9 4101/4885MMP7 4099/4885 |
| US-20210284691-A1 | CBX8 CHROMDOMAIN INHIBITORS AND THE USES THEREOF | CBX8, CBX3, CBX2 | MMP2 4265/4885MMP9 4101/4885MMP7 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.