Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286897 | 0.98 | PTPN1 (0.50) | PTPN1HCRTR1HCRTR2KDM4EMAPT | |
| SCHEMBL9232506 | 0.94 | PTPN1 (0.47) | PTPN1HCRTR1HCRTR2KDM4EMAPT | |
| SCHEMBL8881039 | 0.90 | PTPN1 (0.55) | PTPN1KDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL2271444 | 0.89 | PTPN1 (0.61) | PTPN1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL27480442 | 0.89 | PTPN1 (0.60) | PTPN1KDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL8882025 | 0.88 | PTPN1 (0.62) | PTPN1MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL27883249 | 0.87 | HCRTR1 (0.49) | PTPN1HCRTR1HCRTR2KDM4EMAPT | |
| SCHEMBL126180 | 0.85 | MEN1 (0.54) | PTPN1HCRTR1KDM4EMAPTALDH1A1 | |
| SCHEMBL796628 | 0.84 | KDM4E (0.47) | PTPN1KDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL353286 | 0.84 | MAPT (0.48) | PTPN1HCRTR1HCRTR2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003688-B2 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2011-08-23 | — | — | US | disclosed |
| US-7671086-B2 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUPHARM A/S (DK) | 2010-03-02 | — | — | US | disclosed |
| US-20090227670-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | IMMUPHARM A/S (DK) | 2009-09-10 | — | — | US | disclosed |
| US-7585890-B2 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUNPHARM A/S (DK) | 2009-09-08 | — | — | US | disclosed |
| EP-2089422-A1 | METHODS OF SEPARATING NUCLEIC ACIDS AND PROTEIN | Natimmune A/S (DK) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008106979-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND XYLITOL | IMMUPHARM A/S (DK) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008064686-A1 | METHODS OF SEPARATING NUCLEIC ACIDS AND PROTEIN | NATIMMUNE A/S (DK) | 2008-06-05 | — | — | WO | disclosed |
| EP-1556021-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | IMMUPHARM AS (DK) | 2007-12-19 | — | — | EP | disclosed |
| US-7166640-B2 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2007-01-23 | — | — | US | disclosed |
| US-20060148726-A1 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUPHARM A/S C/O NOVI A/S, NIELS JERNES VEJ 10 (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1307189-B1 | USE OF HYDROXYETHYLRUTOSIDES FOR TREATING SYMPTOMS OF COMMON COLD, ALLERGIC RHINITIS AND INFECTIONS RELATING TO THE RESPIRATORY TRACT | IMMUPHARM APS (DK) | 2006-05-10 | — | — | EP | disclosed |
| US-20050245467-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2005-11-03 | — | — | US | disclosed |
| EP-1556021-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | Immupharm A/S (DK) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037237-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | IMMUPHARM A/S (DK) | 2004-05-06 | — | — | WO | disclosed |
| US-20040053858-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2004-03-18 | — | — | US | disclosed |
| EP-1307189-A2 | METHOD OF TREATING SYMPTOMS OF COMMON COLD, ALLERGIC RHINITIS AND INFECTIONS RELATING TO THE RESPIRATORY TRACT | Immupharm APS (DK) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009699-A2 | METHOD OF TREATING SYMPTOMS OF COMMON COLD, ALLERGIC RHINITIS AND INFECTIONS RELATING TO THE RESPIRATORY TRACT | IMMUPHARM APS (DK) | 2002-02-07 | — | — | WO | disclosed |
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148726-A1 | Pharmaceutical compositions comprising flavonoids and menthol | CHIA, MAVS, C1QBP | PTPN1 3374/4885HCRTR1 2400/4885HCRTR2 3419/4885 |
| US-20050245467-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | CMA1, CHIA, C1QBP | PTPN1 3466/4885HCRTR1 632/4885HCRTR2 672/4885 |
| US-20040053858-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | CMA1, CHIA, C1QBP | PTPN1 3466/4885HCRTR1 632/4885HCRTR2 672/4885 |
| US-20090227670-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | CHIA, MAVS, C1QBP | PTPN1 3374/4885HCRTR1 2400/4885HCRTR2 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.