Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.59 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22764868 | 0.91 | SLC40A1 (0.58) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22764869 | 0.91 | SLC40A1 (0.58) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22765219 | 0.90 | SLC40A1 (0.57) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22765021 | 0.89 | SLC40A1 (0.56) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22765127 | 0.89 | SLC40A1 (0.56) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22765008 | 0.88 | SLC40A1 (0.60) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22765072 | 0.88 | SLC40A1 (0.55) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22764995 | 0.88 | SLC40A1 (0.55) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22764935 | 0.88 | SLC40A1 (0.55) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL22765068 | 0.88 | SLC40A1 (0.55) | SLC40A1GLO1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728194-B1 | QUINOLINE SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | OTAGO INNOVATION LTD (NZ) | 2025-06-04 | — | — | EP | disclosed |
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | OTAGO INNOVATION LIMITED (NZ) | 2023-07-04 | — | — | US | disclosed |
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | OTAGO INNOVATION LIMITED (NZ) | 2023-07-04 | — | — | US | disclosed |
| US-20200385354-A1 | Quinoline Sulfonamide Compounds and Their Use as Antibacterial Agents | OTAGO INNOVATION LIMITED (NZ) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | NQO2, SDHA, SIRT5 | SLC40A1 4081/4885GLO1 369/4885MEN1 4440/4885 |
| US-20200385354-A1 | Quinoline Sulfonamide Compounds and Their Use as Antibacterial Agents | NQO2, SDHA, SIRT5 | SLC40A1 4081/4885GLO1 369/4885MEN1 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.