Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890139 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL1556056 | 0.89 | MAOB (0.54) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL9186019 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL27809104 | 0.82 | MAPK1 (0.52) | ALDH1A1MAOBHTTL3MBTL1TSHR | |
| SCHEMBL7344648 | 0.82 | MAOB (0.50) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL20598466 | 0.80 | MAOB (0.54) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL12815050 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL28416934 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAOBHTTL3MBTL1TSHR | |
| SCHEMBL1759352 | 0.77 | MAOB (0.55) | ALDH1A1HPGDMAOBHTTL3MBTL1 | |
| SCHEMBL28409395 | 0.77 | MAOB (0.51) | ALDH1A1HPGDMAOBHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247605-A1 | COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES | YALE UNIVERSITY (US) | 2020-12-10 | — | — | WO | disclosed |