SCHEMBL9186019

SCHEMBL9186019

N#CCC(=O)OCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.56
HPGD P15428 1/20 0.56
MAOB P27338 1/20 0.48
HTT P42858 1/20 0.46
TSHR P16473 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
F2 P00734 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 1/20 0.41
APP P05067 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29890139 0.85 ALDH1A1 (0.52) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL22766902 0.85 ALDH1A1 (0.52) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL20598466 0.83 MAOB (0.54) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL1556056 0.83 MAOB (0.54) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL28416934 0.82 ALDH1A1 (0.57) ALDH1A1MAOBHTTTSHRKMT2A
SCHEMBL1759352 0.81 MAOB (0.55) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL5583398 0.81 ALDH1A1 (0.57) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL1057912 0.81 MAOB (0.51) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL28409395 0.81 MAOB (0.51) ALDH1A1HPGDMAOBHTTTSHR
SCHEMBL6327015 0.81 MAOB (0.51) ALDH1A1HPGDMAOBHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7097357-A None JP disclosed
JP-H0797357-A MALONIC (P-NITROBENZYL ALCOHOL) ESTER-AMIDE AND ITS PRODUCTION NIPPON KAYAKU CO LTD 1995-04-11 JP disclosed
JP-H00797357-A 0001-01-01 JP disclosed