Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70033 | 0.90 | TNKS (0.50) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL22767270 | 0.82 | ESR1 (0.60) | ALDH1A1NPC1TSHRMEN1KMT2A | |
| SCHEMBL23681041 | 0.81 | ADRB2 (0.54) | ALDH1A1L3MBTL1TSHRKMT2AMAPT | |
| SCHEMBL22767273 | 0.81 | TDP1 (0.53) | GAAALDH1A1NPC1KMT2AMAPT | |
| SCHEMBL13461824 | 0.81 | LMNA (0.61) | GAAALDH1A1NPC1TSHRMAPT | |
| SCHEMBL18671095 | 0.81 | KMT2A (0.49) | ALDH1A1NPC1ALOX15MEN1KMT2A | |
| SCHEMBL11304310 | 0.80 | GAA (0.46) | GAAALDH1A1L3MBTL1NPC1ALOX15 | |
| SCHEMBL907316 | 0.80 | TDP1 (0.59) | GAAALDH1A1L3MBTL1NPC1TSHR | |
| SCHEMBL811579 | 0.79 | GAA (0.66) | GAAALDH1A1L3MBTL1NPC1ALOX15 | |
| SCHEMBL22767268 | 0.79 | HPGD (0.48) | ALDH1A1NPC1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306677-A1 | COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES | YALE UNIVERSITY | 2022-09-29 | — | — | US | disclosed |
| WO-2020247605-A1 | COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES | YALE UNIVERSITY (US) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306677-A1 | COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES | NSUN3, TARBP1, TRDMT1 | GAA 366/4885ALDH1A1 3034/4885L3MBTL1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.