Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 2/20 | 0.66 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508536 | 0.84 | THRB (0.64) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL29474808 | 0.83 | HSPD1 (0.68) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL229763 | 0.83 | HSPD1 (0.68) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL13656899 | 0.81 | MEN1 (0.66) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL30833241 | 0.81 | HSPD1 (0.66) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL14567624 | 0.81 | HPGD (0.58) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL526907 | 0.81 | HSPD1 (0.66) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL5805742 | 0.81 | HSPD1 (0.66) | HSPD1HSPE1KMT2AMEN1HTT | |
| SCHEMBL485235 | 0.80 | HSD17B10 (0.67) | KMT2AMEN1HTTKDM4EHPGD | |
| Metabromsalan SCHEMBL1162534 | 0.79 | HSPD1 (1.00) | HSPD1HSPE1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247756-A1 | SMALL MOLECULES TO RELAX UTERINE SMOOTH MUSCLE CONTRACTIONS | FORCYTE BIOTECHNOLOGIES, INC. (US) | 2020-12-10 | — | — | WO | disclosed |