SCHEMBL229763

SCHEMBL229763

O=C(Nc1ccccc1)c1cc(Br)c(Br)c(Br)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPD1 P10809 2/20 0.68
HSPE1 P61604 2/20 0.68
KMT2A Q03164 7/20 0.53
MEN1 O00255 6/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 2/20 0.53
HPGD P15428 2/20 0.53
KDM4E B2RXH2 1/20 0.53
TP53 P04637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
EGFR P00533 1/20 0.53
ERBB2 P04626 1/20 0.53
CYP1A2 P05177 1/20 0.53
LCK P06239 1/20 0.53
CYP2C9 P11712 1/20 0.53
PTGS1 P23219 1/20 0.53
MAPK1 P28482 1/20 0.53
MAPK14 Q16539 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474808 1.00 HSPD1 (0.68) HSPD1HSPE1KMT2AMEN1LMNA
SCHEMBL30833241 0.98 HSPD1 (0.66) HSPD1HSPE1KMT2AMEN1LMNA
SCHEMBL5805742 0.98 HSPD1 (0.66) HSPD1HSPE1KMT2AMEN1LMNA
SCHEMBL526907 0.98 HSPD1 (0.66) HSPD1HSPE1KMT2AMEN1LMNA
Phosphoric Acid SCHEMBL7515151 0.94 HSPD1 (0.61) HSPD1HSPE1KMT2AMEN1LMNA
Phosphoric Acid SCHEMBL7515153 0.93 HSPD1 (0.59) HSPD1HSPE1KMT2AMEN1LMNA
SCHEMBL28497138 0.83 HSPD1 (0.58) HSPD1HSPE1KMT2AMEN1LMNA
SCHEMBL22767660 0.83 HSPD1 (0.66) HSPD1HSPE1KMT2AMEN1LMNA
SCHEMBL3441192 0.82 HSPD1 (0.60) HSPD1HSPE1KMT2AMEN1LMNA
Metabromsalan SCHEMBL1162534 0.81 HSPD1 (1.00) HSPD1HSPE1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 774 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111526873-B For modulating microbial colonization substituted diphenylacetylenes of (2) 生物曼迪克斯有限责任公司 2025-03-04 CN claimed
WO-2024064209-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY, INC. (US) 2024-03-28 WO claimed
US-20230323279-A1 MUTANT ALGAE, METHOD OF PREPARATION AND APPLICATION THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2023-10-12 US claimed
EP-3644955-B1 PERSONAL CARE COMPOSITIONS COMPRISING A 2-PYRIDINOL N-OXIDE MATERIAL AND AN IRON CHELATOR PROCTER & GAMBLE (US) 2023-03-15 EP claimed
CN-112666271-B Method for detecting organic pollutants in honey 宁波检验检疫科学技术研究院 2022-10-14 CN claimed
CN-111533970-B Mildew-proof antibacterial rubber and plastic product and preparation method thereof 神州节能科技集团有限公司 2022-03-11 CN claimed
CN-114085568-A Mixed vegetable oil-based screen printing ink, preparation method thereof and screen printing process 东莞高绮印刷有限公司 2022-02-25 CN claimed
CN-112666271-A Reagent pack for universal pretreatment of organic pollutants in honey, method and detection application thereof 宁波检验检疫科学技术研究院 2021-04-16 CN claimed
CN-112480597-A Preparation method of mildew-proof antibacterial rubber and plastic product 无锡市东北塘永丰橡塑厂 2021-03-12 CN claimed
CN-111533970-A Mildew-proof antibacterial rubber and plastic product and preparation method thereof 神州节能科技集团有限公司 2020-08-14 CN claimed
WO-1998016194-A1 PERFUMED PRODUCTS QUEST INTERNATIONAL B.V. (NL) 1998-04-23 WO claimed
CN-1102207-A High-grade specific bactericidal and detoxicating washing powder LIAO SHANG (CN) 1995-05-03 CN claimed
US-5103500-A Odor suppressing disposable garment shield NAGER FRANK B (US) 1992-04-14 US claimed
US-4517919-A Animal litter composition THE PROCTER & GAMBLE COMPANY (US) 1985-05-21 US claimed
US-4494482-A Animal litter composition THE PROCTER & GAMBLE COMPANY (US) 1985-01-22 US claimed
EP-0109275-A2 Animal litter composition THE PROCTER & GAMBLE COMPANY (US) 1984-05-23 EP claimed
US-4294852-A WATER, AN ALIPHATIC ALCOHOL AND AN ORGANIC ACID TO ADJUST THE PH OF THE VEHICLE JOHNSON & JOHNSON (US) 1981-10-13 US claimed
US-4040956-A SEWAGE DISPOSAL USING RECIRCULATABLE CYCLOHEXYL-C12 TO C14 ALKANES GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-08-09 US claimed
US-4018888-A Amine-stabilized dry powder aerosol antiperspirant compositions and method of preparation THE PROCTER & GAMBLE COMPANY (US) 1977-04-19 US claimed
US-4018887-A Amide-stabilized dry powder aerosol antiperspirant compositions and method of preparation THE PROCTER & GAMBLE COMPANY (US) 1977-04-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230323279-A1 MUTANT ALGAE, METHOD OF PREPARATION AND APPLICATION THEREOF STOM, PPA1, ALAD HSPD1 2132/4885HSPE1 3180/4885KMT2A 1988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.