Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.31 |
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365105 | 0.83 | DPP7 (0.35) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL22769065 | 0.79 | DPP7 (0.43) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL13456304 | 0.79 | DPP7 (0.43) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL20653680 | 0.79 | DPP7 (0.43) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL24481893 | 0.78 | EPHX1 (0.33) | EPHX1KISS1R | |
| SCHEMBL19504757 | 0.77 | KISS1R (0.40) | DPP7EPHX1KISS1RHTR2AHRH1 | |
| SCHEMBL432790 | 0.75 | GSR (0.57) | NOS2NOS1NOS3CYP1A2CYP3A4 | |
| SCHEMBL1104625 | 0.75 | KISS1R (0.47) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL12825453 | 0.75 | KISS1R (0.47) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL14947748 | 0.75 | KISS1R (0.47) | DPP7EPHX1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247297-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2020-12-10 | — | — | WO | disclosed |