SCHEMBL19504757

SCHEMBL19504757

C=C(C)C(N)CCCNC

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KISS1R Q969F8 1/20 0.40
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
DPP7 Q9UHL4 1/20 0.32
DDAH1 O94760 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22365105 0.94 DPP7 (0.35) KISS1RHTR2AHRH1DPP7EPHX1
SCHEMBL21342734 0.83 ALOX15 (0.34) DPP7
SCHEMBL25670405 0.82 DPP7 (0.37) DPP7DDAH1
SCHEMBL21479782 0.81 DPP7 (0.39) DPP7DDAH1
SCHEMBL19540943 0.79 CYP2C19 (0.41) DPP7
SCHEMBL16602285 0.78 KISS1R (0.53) KISS1RHTR2AHRH1DPP7
SCHEMBL13776588 0.78 KISS1R (0.53) KISS1RHTR2AHRH1DPP7
SCHEMBL15132881 0.78 KISS1R (0.53) KISS1RHTR2AHRH1DPP7
SCHEMBL23568898 0.78 DDAH1 (0.32) DPP7DDAH1
SCHEMBL22769062 0.77 DPP7 (0.35) KISS1RHTR2AHRH1DPP7DDAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017184529-A1 ANTISENSE OLIGOMERS AND METHODS OF USING THE SAME FOR TREATING DISEASES ASSOCIATED WITH THE ACID ALPHA-GLUCOSIDASE GENE SAREPTA THERAPEUTICS, INC. (US) 2017-10-26 WO disclosed