Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.44 |
| ▸ | PYGB | P11216 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713747 | 0.93 | IGF2R (0.41) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL16644773 | 0.90 | GJB2 (0.44) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL29415375 | 0.90 | IGF2R (0.49) | IGF2RLGALS8LGALS3LGALS4MAOB | |
| SCHEMBL17776041 | 0.90 | MMP13 (0.42) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL15133472 | 0.89 | PYGB (0.51) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL21845982 | 0.89 | GAA (0.43) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL21845897 | 0.89 | GAA (0.43) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL17451459 | 0.89 | PYGB (0.51) | IGF2RGAALGALS8LGALS3LGALS4 | |
| SCHEMBL16092079 | 0.88 | GJB2 (0.46) | IGF2RLGALS8LGALS3LGALS4MAPK1 | |
| SCHEMBL16640877 | 0.88 | GJB2 (0.46) | IGF2RGAALGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247297-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2020-12-10 | — | — | WO | disclosed |