⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976403 | 0.79 | — | — | |
| SCHEMBL11041636 | 0.77 | F2R (0.32) | — | |
| SCHEMBL28974200 | 0.76 | NAMPT (0.33) | — | |
| SCHEMBL1303381 | 0.76 | — | — | |
| SCHEMBL28976574 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL6347415 | 0.72 | — | — | |
| SCHEMBL21690925 | 0.72 | — | — | |
| SCHEMBL2038041 | 0.72 | — | — | |
| SCHEMBL31121771 | 0.70 | LMNA (0.39) | — | |
| SCHEMBL10443636 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237410-B1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2020-12-16 | — | — | EP | disclosed |
| CN-107428749-B | Substituted imidazo [1,2- α ] pyridin-2-ylamine compounds, pharmaceutical compositions and methods of use thereof | 上海复旦张江生物医药股份有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-107428749-A | The substituted ylamine compounds of imidazo [1,2 α] pyridine 2 and its pharmaceutical composition and application method | 南京泽宁医药研发有限公司 | 2017-12-01 | — | — | CN | disclosed |