SCHEMBL28974200

SCHEMBL28974200

[CH2]NC(=O)CCC(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28976953 0.80 ALDH1A1 (0.33)
SCHEMBL22769448 0.76
SCHEMBL1578791 0.74 KDM4E (0.50) NAMPT
SCHEMBL9363475 0.74 LMNA (0.48) NAMPT
SCHEMBL27573501 0.72 KDM4E (0.48) NAMPT
Hydrochloric Acid SCHEMBL19136144 0.72 KDM4E (0.48) NAMPT
SCHEMBL3589092 0.71 HTT (0.31) NAMPT
SCHEMBL20004059 0.70 TSHR (0.63)
SCHEMBL24380469 0.70
SCHEMBL19200702 0.70 FAAH (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867348-A Imidazopyrimidines as IL-17 modulators 詹森药业有限公司 2023-03-28 CN disclosed