Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18297574 | 0.92 | APP (0.60) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6749775 | 0.86 | ALOX5 (0.67) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL339813 | 0.85 | LMNA (0.82) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27367676 | 0.85 | LMNA (0.82) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28385012 | 0.85 | MEN1 (0.54) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL4768681 | 0.84 | MAOB (0.49) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14786201 | 0.83 | MAOB (0.71) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14786200 | 0.83 | MAOB (0.71) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28396179 | 0.82 | LMNA (0.60) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8773557 | 0.82 | LMNA (0.60) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322644-B | Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-02 | — | — | CN | claimed |
| CN-115322644-A | Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-11-11 | — | — | CN | claimed |
| EP-0690855-B1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LTD (GB) | 1996-12-18 | — | — | EP | claimed |
| CN-115322644-B | Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-115322644-A | Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-11-11 | — | — | CN | disclosed |
| CN-108368107-B | Fused heterocyclic compounds as S1P modulators | 艾伯维公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-111807938-A | (E) -1-chloro-2-iodoethylene compound and preparation method thereof | 盐城工学院 | 2020-10-23 | — | — | CN | disclosed |
| CN-107406424-B | Estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-106536679-B | Liquid-crystalline medium with homeotropic alignment | 默克专利股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| EP-3233828-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-03-04 | — | — | EP | disclosed |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2004069843-A1 | NOVEL TRICYCLIC AZEPINE DERIVATIVES, METHOD FOR PRODUCTION THEROF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LES LABORATOIRES SERVIER (FR) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5559144-A | LIPOXYGENASE INHIBITORS, INHIBITORS OF BIOSYNTHESIS OF LEUKOTRIENES | ABBOTT LABORATORIES (US) | 1996-09-24 | — | — | US | disclosed |
| US-5476873-A | Inhibit biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0540673-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0540673-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | ABBOTT LAB (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001682-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1992-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | S1PR1, S1PR2, S1PR3 | MAOB 3377/4885LMNA 2307/4885CYP1A2 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.