Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | USP8 | P40818 | 7/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22772263 | 0.88 | USP8 (0.51) | ALDH1A1CYP3A4CYP2C19USP8TERT | |
| SCHEMBL22772270 | 0.86 | TERT (0.50) | ALDH1A1CYP3A4MAPTCYP2C9HPGD | |
| SCHEMBL21668603 | 0.80 | ABCG2 (0.49) | ALDH1A1CYP3A4MAPTHPGDUSP8 | |
| SCHEMBL21647149 | 0.78 | CYP3A4 (0.63) | ALDH1A1CYP3A4MAPTCYP2C9HPGD | |
| SCHEMBL22789455 | 0.77 | MAOA (0.44) | ALDH1A1CYP3A4MAPTCYP2C9HPGD | |
| SCHEMBL21647176 | 0.74 | USP8 (0.72) | CYP3A4CYP2C19USP8TERTCCNT1 | |
| SCHEMBL21647173 | 0.74 | TERT (0.66) | ALDH1A1CYP3A4MAPTCYP2C9HPGD | |
| SCHEMBL22772252 | 0.72 | TERT (0.42) | ALDH1A1CYP3A4MAPTCYP2C9HPGD | |
| SCHEMBL21668602 | 0.72 | ABCG2 (0.47) | ALDH1A1CYP3A4MAPTHPGDUSP8 | |
| SCHEMBL22772266 | 0.70 | TERT (0.62) | ALDH1A1CYP3A4MAPTCYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831821-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | Shaanxi Micot Technology Limited Company (CN) | 2021-06-09 | — | — | EP | disclosed |
| US-20200390755-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390755-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | MAPT, PYGB, SLC6A2 | ALDH1A1 787/4885CYP3A4 184/4885MAPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.