Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206442 | 0.92 | PRKCA (0.37) | PRKCAMMP12 | |
| SCHEMBL2277316 | 0.89 | PRKCA (0.34) | PRKCAMMP12 | |
| SCHEMBL2279364 | 0.87 | PRKCA (0.44) | PRKCAMMP12 | |
| SCHEMBL2276552 | 0.84 | PRKCA (0.54) | PRKCAMMP12 | |
| SCHEMBL2279362 | 0.82 | PRKCA (0.47) | PRKCAMMP12 | |
| SCHEMBL2278878 | 0.80 | PRKCA (0.43) | PRKCAMMP12ACACBACACA | |
| SCHEMBL2275227 | 0.76 | PRKCA (0.47) | PRKCAMMP12 | |
| SCHEMBL2279343 | 0.74 | PRKCA (0.42) | PRKCAMMP12ACACBACACA | |
| SCHEMBL4223402 | 0.73 | PRKCA (0.57) | PRKCAMMP12 | |
| SCHEMBL3685055 | 0.73 | PRKCA (0.57) | PRKCAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989438-B2 | Therapeutic compounds | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-02 | — | — | US | disclosed |