Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218773 | 0.91 | PRKCA (0.44) | PRKCAMMP12OPRM1OPRK1OPRD1 | |
| SCHEMBL2279340 | 0.89 | PRKCA (0.42) | PRKCAMMP12OPRM1OPRK1OPRD1 | |
| SCHEMBL2276740 | 0.84 | PRKCA (0.49) | PRKCAMMP12OPRM1OPRK1CNR2 | |
| SCHEMBL2276676 | 0.83 | PRKCA (0.63) | PRKCAMMP12OPRM1OPRK1OPRD1 | |
| SCHEMBL2281023 | 0.81 | PRKCA (0.55) | PRKCAMMP12OPRM1OPRK1CNR2 | |
| SCHEMBL2276362 | 0.81 | PRKCA (0.56) | PRKCAMMP12OPRM1OPRK1CNR2 | |
| SCHEMBL2276737 | 0.79 | PRKCA (0.49) | PRKCAMMP12OPRM1OPRK1CNR2 | |
| SCHEMBL2278878 | 0.79 | PRKCA (0.43) | PRKCAMMP12HTR4ACACBACACA | |
| SCHEMBL394843 | 0.77 | PRKCA (0.61) | PRKCAMMP12CNR2ACACBACACA | |
| SCHEMBL2277321 | 0.74 | PRKCA (0.35) | PRKCAMMP12ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989438-B2 | Therapeutic compounds | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-02 | — | — | US | disclosed |