SCHEMBL22775948

SCHEMBL22775948

CCSc1nn2c(C)cc(C)nc2c1-c1nc2cc(C(F)(F)F)ncc2n1C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 10/20 0.42
▸ KDM4E B2RXH2 4/20 0.38
▸ POLB P06746 3/20 0.38
▸ CYP1A2 P05177 1/20 0.34
▸ HPGD P15428 2/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ CRHR1 P34998 1/20 0.30
▸ GRM8 O00222 1/20 0.30
▸ GRM7 Q14831 1/20 0.30
▸ GRM4 Q14833 1/20 0.30
▸ PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29526330 1.00 HTR6 (0.42) HTR6KDM4EPOLBCYP1A2HPGD
SCHEMBL28683393 0.88 HTR6 (0.33) HTR6PTGS2
SCHEMBL19993342 0.85 KDM4E (0.36) HTR6KDM4EPOLBCYP1A2MEN1
SCHEMBL22775859 0.82 KDM4E (0.38) HTR6KDM4EPOLBALDH1A1MEN1
SCHEMBL29525495 0.82 KDM4E (0.38) HTR6KDM4EPOLBALDH1A1MEN1
SCHEMBL22776118 0.82 POLB (0.45) HTR6KDM4EPOLBCYP1A2HPGD
SCHEMBL22776126 0.80 HTR6 (0.32) HTR6
SCHEMBL29525651 0.80 HTR6 (0.32) HTR6
SCHEMBL29525628 0.79 ATR (0.34) —
SCHEMBL22776008 0.79 NPSR1 (0.33) KDM4EHPGDALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3983411-B1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD (IN) 2026-05-27 — — EP claimed
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents PI INDUSTRIES LTD (IN) 2025-08-12 — — US claimed
CN-114008043-B Condensed heterocyclic compounds and their use as pest control agents PI工业有限公司 2024-06-07 — — CN claimed
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2022-08-11 — — US claimed
EP-3983411-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI Industries Ltd. (IN) 2022-04-20 — — EP claimed
CN-114008043-A Fused heterocyclic compound and use thereof as pest control agent PI工业有限公司 2022-02-01 — — CN claimed
WO-2020250183-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2020-12-17 — — WO claimed
EP-3983411-B1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD (IN) 2026-05-27 — — EP disclosed
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents PI INDUSTRIES LTD (IN) 2025-08-12 — — US disclosed
CN-114008043-B Condensed heterocyclic compounds and their use as pest control agents PI工业有限公司 2024-06-07 — — CN disclosed
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2022-08-11 — — US disclosed
EP-3983411-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI Industries Ltd. (IN) 2022-04-20 — — EP disclosed
CN-114008043-A Fused heterocyclic compound and use thereof as pest control agent PI工业有限公司 2022-02-01 — — CN disclosed
WO-2020250183-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2020-12-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents DDT, ACHE, KEAP1 HTR6 3700/4885KDM4E 160/4885POLB 4600/4885
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS DDT, ACHE, KEAP1 HTR6 3700/4885KDM4E 160/4885POLB 4600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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