SCHEMBL2277795

SCHEMBL2277795

COc1c(C=O)cccc1OBOc1cccc(C=O)c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
TLR2 O60603 1/20 0.51
ERN1 O75460 1/20 0.51
TLR1 Q15399 1/20 0.51
TLR6 Q9Y2C9 1/20 0.51
SRC P12931 1/20 0.51
NFE2L2 Q16236 5/20 0.46
CYP1A2 P05177 3/20 0.45
LMNA P02545 2/20 0.45
ALDH1A1 P00352 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
PRMT1 Q99873 1/20 0.44
HPGD P15428 2/20 0.42
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CYP1A1 P04798 2/20 0.41
CYP1B1 Q16678 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Veratraldehyde SCHEMBL28289918 0.85 SRC (0.67) CA1CA2TLR2ERN1TLR1
O-Veratraldehyde SCHEMBL29923149 0.85 SRC (0.67) CA1CA2TLR2ERN1TLR1
O-Veratraldehyde SCHEMBL319070 0.85 SRC (0.67) CA1CA2TLR2ERN1TLR1
SCHEMBL2787203 0.80 CA1 (0.73) CA1CA2TLR2ERN1TLR1
SCHEMBL12377005 0.80 CA1 (0.58) CA1CA2TLR2ERN1TLR1
O-Veratraldehyde SCHEMBL8706125 0.79 SRC (0.59) CA1CA2TLR2ERN1TLR1
O-Veratraldehyde SCHEMBL28143507 0.79 SRC (0.64) CA1CA2TLR2ERN1TLR1
SCHEMBL3638137 0.77 CA1 (0.54) CA1CA2TLR2ERN1TLR1
SCHEMBL30385316 0.77 CA1 (0.59) CA1CA2TLR2ERN1TLR1
SCHEMBL18196756 0.77 CA1 (0.59) CA1CA2TLR2ERN1TLR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4588927-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2025-07-23 EP disclosed
US-20240423085-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-12-19 US disclosed
CN-119019459-A Organic electroluminescent material and device 环球展览公司 2024-11-26 CN disclosed
US-20240090311-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-03-14 US disclosed
CN-116903664-A Organic electroluminescent material and device 环球展览公司 2023-10-20 CN disclosed
US-7989438-B2 Therapeutic compounds ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2011-08-02 US disclosed
WO-2010082050-A1 MACROCYCLIC AND 7-AMINOALKYL-SUBSTITUTED BENZOXAZOCINES FOR TREATMENT OF HEPATITIS C INFECTIONS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2010-07-22 WO disclosed
EP-2178886-A1 MACROCYCLIC INDOLE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C INFECTIONS Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. (IT) 2010-04-28 EP disclosed
EP-2178885-A1 MACROCYCLIC INDOLE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C INFECTIONS Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. (IT) 2010-04-28 EP disclosed
US-20090048239-A1 Therapeutic compounds MSD ITALIA S.R.L. (IT) 2009-02-19 US disclosed
WO-2009010783-A1 MACROCYCLIC INDOLE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C INFECTIONS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2009-01-22 WO disclosed
WO-2009010785-A1 MACROCYCLIC INDOLE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C INFECTIONS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2009-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048239-A1 Therapeutic compounds RRP1B, RCE1, CTSZ CA1 4330/4885CA2 4645/4885TLR2 4035/4885
US-20240423085-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OPRM1 CA1 2710/4885CA2 2808/4885TLR2 3785/4885
US-20240090311-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 CA1 2392/4885CA2 2315/4885TLR2 2604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.