Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 5/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22381396 | 0.84 | PGR (0.67) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22020755 | 0.81 | ERN1 (0.56) | FYNCHEK2CHEK1POLBTGFBR1 | |
| SCHEMBL27625890 | 0.80 | ERN1 (0.57) | FYNCHEK2CHEK1POLBPGR | |
| SCHEMBL28036688 | 0.79 | CA1 (0.43) | FYNCHEK2ABL1APPTGFBR1 | |
| SCHEMBL16581413 | 0.78 | POLB (0.59) | FYNCHEK1POLBAPPGAA | |
| SCHEMBL21815270 | 0.78 | CA1 (0.55) | FYNPIM1MAOBCA1CA2 | |
| SCHEMBL3693339 | 0.78 | MAOB (0.67) | FYNPOLBGAAMAOBCA2 | |
| SCHEMBL10893692 | 0.78 | MCL1 (0.56) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL526920 | 0.77 | ALDH1A1 (0.56) | ABL1CA1CA2TP53TSHR | |
| SCHEMBL29431716 | 0.77 | ALDH1A1 (0.56) | ABL1CA1CA2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252217-A1 | BIO-BASED POLYSULFONES AND USES THEREOF | EPPS THOMAS H III (US) | 2020-12-17 | — | — | WO | claimed |
| WO-2020252217-A1 | BIO-BASED POLYSULFONES AND USES THEREOF | EPPS THOMAS H III (US) | 2020-12-17 | — | — | WO | disclosed |