Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25964107 | 0.86 | HIF1A (0.37) | HIF1AHSD17B10NOS2NOS3NOS1 | |
| SCHEMBL21090095 | 0.83 | HIF1A (0.38) | HIF1AHSD17B10NOS2NOS3NOS1 | |
| SCHEMBL18735919 | 0.83 | — | — | |
| SCHEMBL18464548 | 0.83 | HIF1A (0.38) | HIF1AHSD17B10NOS2NOS3NOS1 | |
| SCHEMBL25972536 | 0.79 | SLC6A2 (0.39) | HIF1AHSD17B10SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4360524 | 0.79 | SLC6A2 (0.39) | HIF1AHSD17B10SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19407944 | 0.79 | HIF1A (0.36) | HIF1AHSD17B10NOS2NOS3NOS1 | |
| SCHEMBL1132940 | 0.77 | — | — | |
| SCHEMBL4308213 | 0.77 | — | — | |
| SCHEMBL16165636 | 0.76 | SLC6A3 (0.35) | HIF1AHSD17B10NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219516-A2 | CHIRAL CONTROL | Wave Life Sciences Ltd. (SG) | 2023-08-02 | — | — | EP | disclosed |
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |
| EP-3812370-A1 | ASYMMETRIC AUXILIARY GROUP | Wave Life Sciences Ltd. (SG) | 2021-04-28 | — | — | EP | disclosed |
| EP-2872485-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2020-12-16 | — | — | EP | disclosed |