Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22795866 | 0.64 | — | — | |
| SCHEMBL12107535 | 0.64 | RIPK1 (0.31) | — | |
| SCHEMBL17341934 | 0.60 | GAA (0.30) | GAATDP1 | |
| SCHEMBL20663324 | 0.58 | PRKCZ (0.41) | GAATDP1KDM4EL3MBTL1 | |
| SCHEMBL23137861 | 0.57 | — | — | |
| SCHEMBL21040590 | 0.55 | OPRK1 (0.31) | — | |
| SCHEMBL22062337 | 0.54 | — | — | |
| SCHEMBL19997520 | 0.51 | — | — | |
| SCHEMBL29300083 | 0.51 | — | — | |
| SCHEMBL10213112 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307258-B1 | ARYL SULFONOHYDRAZIDES | UNIV MONASH (AU) | 2020-12-16 | — | — | EP | disclosed |