Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20545450 | 0.88 | KDM4E (0.36) | DDR1TRPA1TRPV4ADORA2A | |
| SCHEMBL22349370 | 0.86 | DDR1 (0.37) | DDR1TRPA1TRPV4MPLPKM | |
| SCHEMBL22291718 | 0.82 | DDR1 (0.34) | DDR1ADORA2A | |
| SCHEMBL22779574 | 0.80 | TDP2 (0.36) | DDR1TRPA1 | |
| SCHEMBL22779591 | 0.78 | PDE10A (0.32) | DDR1 | |
| SCHEMBL18073398 | 0.78 | GSR (0.33) | DDR1PKMADORA2A | |
| SCHEMBL18073404 | 0.76 | KDR (0.34) | DDR1PKMADORA2AHSD11B1 | |
| SCHEMBL23971752 | 0.74 | DDR1 (0.30) | DDR1 | |
| SCHEMBL20581691 | 0.74 | BRD4 (0.31) | DDR1 | |
| SCHEMBL20505439 | 0.74 | ALDH1A1 (0.30) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3317276-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-16 | — | — | EP | disclosed |