Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291717 | 0.91 | DDR1 (0.32) | DDR1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL21571469 | 0.87 | MEN1 (0.30) | DDR1MEN1KMT2A | |
| SCHEMBL20545450 | 0.85 | KDM4E (0.36) | DDR1ADORA2A | |
| SCHEMBL18073398 | 0.84 | GSR (0.33) | DDR1ADORA2AMEN1KMT2A | |
| SCHEMBL18357969 | 0.83 | DDR1 (0.35) | DDR1 | |
| SCHEMBL22779574 | 0.82 | TDP2 (0.36) | DDR1 | |
| SCHEMBL22779521 | 0.82 | DDR1 (0.38) | DDR1ADORA2A | |
| SCHEMBL22779591 | 0.82 | PDE10A (0.32) | DDR1 | |
| SCHEMBL23971752 | 0.80 | DDR1 (0.30) | DDR1 | |
| SCHEMBL20505439 | 0.80 | ALDH1A1 (0.30) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377489-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-07 | — | — | EP | disclosed |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
| US-10730872-B2 | Pesticidally active heterocyclic derivatives with sulphur containing sustitutents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730872-B2 | Pesticidally active heterocyclic derivatives with sulphur containing sustitutents | TST, DDT, SULT1A1 | DDR1 2408/4885L3MBTL1 1380/4885ADORA2A 2180/4885 |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | DDR1 4468/4885L3MBTL1 1417/4885ADORA2A 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.