Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16013633 | 0.75 | SCN9A (0.51) | — | |
| SCHEMBL16013368 | 0.75 | FPR2 (0.37) | PTGER1 | |
| SCHEMBL856019 | 0.66 | ERN1 (0.55) | L3MBTL1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL6593582 | 0.64 | BRD4 (0.56) | LMNAKDM4EL3MBTL1MAPTHTT | |
| SCHEMBL3370688 | 0.62 | LMNA (0.50) | LMNAKDM4EL3MBTL1MAPTHTT | |
| SCHEMBL4481351 | 0.62 | ERN1 (0.51) | LMNAL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL31113771 | 0.62 | ERN1 (0.54) | L3MBTL1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL31167060 | 0.62 | KDM1A (0.44) | L3MBTL1MAPTMAPK1TDP1MRGPRX4 | |
| SCHEMBL24446054 | 0.62 | MAPT (0.53) | L3MBTL1MAPTHTTMAPK1TDP1 | |
| SCHEMBL5033252 | 0.61 | MAPT (0.50) | FFAR1LMNAL3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293184-B1 | PYRIMIDINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2020-12-16 | — | — | EP | disclosed |