SCHEMBL22780296

SCHEMBL22780296

c1ccc2c(c1)-c1ccc(-c3ccc(N(c4ccc(-c5cccc6c5oc5ccccc56)cc4)c4ccc5ccccc5c4)cc3)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
PRKDC P78527 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22787900 0.97 ALOX5 (0.37) ALOX5PRKDC
SCHEMBL23621664 0.93 ALOX5 (0.37) ALOX5PRKDC
SCHEMBL22780194 0.92 ALOX5 (0.39) ALOX5PRKDC
SCHEMBL23333818 0.91 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL22780088 0.91 ALDH1A1 (0.30)
SCHEMBL22787930 0.91
SCHEMBL22779990 0.90 ALOX5 (0.39) ALOX5PRKDC
SCHEMBL22780164 0.90 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL22787901 0.89 ALOX5 (0.39) ALOX5PRKDC
SCHEMBL22780104 0.89 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985324-B2 Nitrogen-containing compound, organic electroluminescent device and photoelectric conversion device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2021-04-20 US disclosed
WO-2020248755-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND PHOTOELECTRIC CONVERSION DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed
US-20200395544-A1 Nitrogen-containing compound, organic electroluminescent device and photoelectric conversion device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2020-12-17 US disclosed
EP-3750875-A2 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND PHOTOELECTRIC CONVERSION DEVICE Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2020-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200395544-A1 Nitrogen-containing compound, organic electroluminescent device and photoelectric conversion device NOS1, NOM1, NUDC ALOX5 1363/4885PRKDC 3387/4885
US-10985324-B2 Nitrogen-containing compound, organic electroluminescent device and photoelectric conversion device NOS1, NOM1, NUDC ALOX5 1363/4885PRKDC 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.