Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27628922 | 0.85 | KDM4E (0.62) | KDM4EHSD17B10MAOAALDH1A1GAA | |
| SCHEMBL2450078 | 0.84 | KDM4E (0.71) | KDM4EHSD17B10MAOAALDH1A1GAA | |
| SCHEMBL5472418 | 0.82 | HSD17B10 (0.54) | KDM4EHSD17B10MAOAALDH1A1GAA | |
| SCHEMBL1660191 | 0.78 | GAA (0.63) | KDM4EHSD17B10MAOAALDH1A1GAA | |
| SCHEMBL15116253 | 0.78 | ALDH1A1 (0.50) | KDM4EHSD17B10ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL17861953 | 0.78 | NQO1 (0.51) | KDM4EHSD17B10ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5532851 | 0.77 | KDM4E (0.73) | KDM4EHSD17B10MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL29515065 | 0.77 | GAA (0.69) | KDM4EHSD17B10ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL565925 | 0.77 | GAA (0.69) | KDM4EHSD17B10ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19378623 | 0.77 | KDM4E (0.58) | KDM4EHSD17B10MAOAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303326-B1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-12-16 | — | — | EP | disclosed |
| CN-104428036-A | Polypeptides and their use | NOVABIOTICS LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-101910136-B | Fluorescent agent having ethynyl group | NIPPON CHEMICAL WORKS | 2012-08-15 | — | — | CN | disclosed |
| CN-101910136-A | Fluorescent agent having ethynyl group | NIPPON CHEMICAL WORKS | 2010-12-08 | — | — | CN | disclosed |
| CN-101501015-A | Use of coumarin derivatives in antifungal therapy | NOVABIOTICS LTD (GB) | 2009-08-05 | — | — | CN | disclosed |