Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264037 | 0.77 | LTA4H (0.45) | TAAR1LTA4HALDH1A1KCNA3HRH1 | |
| SCHEMBL14983318 | 0.74 | LTA4H (0.52) | LTA4HALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL465983 | 0.74 | TAAR1 (0.54) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 | |
| SCHEMBL6660834 | 0.72 | TAAR1 (0.52) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 | |
| SCHEMBL7416230 | 0.71 | KCNA3 (0.44) | TAAR1LTA4HALDH1A1TSHRKCNA3 | |
| SCHEMBL93572 | 0.71 | TAAR1 (0.50) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 | |
| SCHEMBL28466216 | 0.70 | KDM4E (0.58) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 | |
| Monoethanolamine SCHEMBL4159313 | 0.70 | ALDH1A1 (0.43) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 | |
| SCHEMBL43067 | 0.69 | TAAR1 (1.00) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 | |
| Bromide SCHEMBL2762682 | 0.67 | TAAR1 (0.95) | TAAR1LTA4HPLA2G2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189310-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2011-08-04 | — | — | US | claimed |
| WO-2010042728-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2010-04-15 | — | — | WO | claimed |
| US-20110189310-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
| WO-2010042728-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2010-04-15 | — | — | WO | disclosed |