SCHEMBL22784145

SCHEMBL22784145

N#Cc1c(Cl)c(NCCc2ccccc2)c(NCCc2ccccc2)c(Cl)c1C#N

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
TAAR1 Q96RJ0 1/20 0.57
NRP1 O14786 16/20 0.50
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27691514 0.73 TAAR1 (0.58) ALDH1A1SMN1; SMN2TAAR1L3MBTL1MEN1
SCHEMBL23162580 0.73 TAAR1 (0.56) ALDH1A1SMN1; SMN2TAAR1NRP1KDM4E
SCHEMBL22784150 0.70 NPC1 (0.41) ALDH1A1SMN1; SMN2TAAR1
SCHEMBL6350074 0.70 NRP1 (0.49) ALDH1A1SMN1; SMN2TAAR1NRP1L3MBTL1
SCHEMBL22784143 0.69 CCNC (0.51) ALDH1A1SMN1; SMN2TAAR1L3MBTL1MEN1
SCHEMBL14325881 0.67 ADORA2A (0.44) ALDH1A1SMN1; SMN2L3MBTL1MEN1KMT2A
SCHEMBL10395199 0.66 SMN1; SMN2 (0.64) ALDH1A1SMN1; SMN2TAAR1L3MBTL1KDM4E
SCHEMBL2243709 0.66 NPC1 (0.52) ALDH1A1SMN1; SMN2TAAR1L3MBTL1KDM4E
SCHEMBL30673004 0.66 MEN1 (0.62) SMN1; SMN2L3MBTL1MEN1KMT2AKDM4E
SCHEMBL3907119 0.66 L3MBTL1 (0.53) ALDH1A1SMN1; SMN2TAAR1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200392343-A1 COMPOSITION, CURED PRODUCT, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-17 US disclosed