Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904040 | 0.84 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2MAPTPKMRAB9A | |
| SCHEMBL9421891 | 0.83 | MAPT (0.52) | SMN1; SMN2MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL9837512 | 0.80 | PBRM1 (0.54) | SMN1; SMN2MAPTPKMRAB9ANPC1 | |
| SCHEMBL2316630 | 0.79 | HSD17B10 (0.59) | L3MBTL1MAPTPKMMAPK14ALDH1A1 | |
| SCHEMBL23198328 | 0.79 | CCNC (0.45) | L3MBTL1SMN1; SMN2MAPTPKMRAB9A | |
| SCHEMBL3711850 | 0.79 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2MAPTPKMRAB9A | |
| SCHEMBL11505439 | 0.77 | MAPT (0.47) | SMN1; SMN2MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL8150179 | 0.77 | MAPT (0.58) | L3MBTL1SMN1; SMN2MAPTPKMRAB9A | |
| SCHEMBL6032214 | 0.76 | L3MBTL1 (0.53) | L3MBTL1SMN1; SMN2MAPTPKMRAB9A | |
| SCHEMBL3910980 | 0.76 | L3MBTL1 (0.59) | L3MBTL1SMN1; SMN2MAPTPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101585774-B | Synthetic method of N-aralkyl anilines compound | UNIV SOUTHWEST | 2013-01-09 | — | — | CN | disclosed |
| CN-101585774-A | Synthetic method of N-aralkyl anilines compound | UNIV SOUTHWEST (CN) | 2009-11-25 | — | — | CN | disclosed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| CN-87100686-A | 3-alkoxyl group-2-aminopropylamines as cardiovascular agents | — | 1987-10-14 | — | — | CN | disclosed |