SCHEMBL2278424

SCHEMBL2278424

CC(C)CC(C)Cc1ccc(C(=O)O)c(C(=O)O)c1CC(C)CC(C)C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.33
MEN1 O00255 3/20 0.33
HPGD P15428 3/20 0.33
KMT2A Q03164 3/20 0.33
AKR1C2 P52895 2/20 0.33
CRHBP P24387 2/20 0.33
HTT P42858 2/20 0.33
CRHR2 Q13324 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
AKR1C1 Q04828 1/20 0.33
ALOX5 P09917 2/20 0.32
PTGES O14684 1/20 0.32
PTGS1 P23219 3/20 0.32
PTGS2 P35354 3/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP2C9 P11712 2/20 0.32
AKR1C3 P42330 2/20 0.32
CXCR1 P25024 2/20 0.32
CXCR2 P25025 2/20 0.32
ALB P02768 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446930 0.86 MAPT (0.36) LMNAMEN1HPGDKMT2AAKR1C2
SCHEMBL4215205 0.86 ALDH1A1 (0.31) AKR1C2AKR1C1ALDH1A1
SCHEMBL77326 0.84 LMNA (0.39) LMNAMEN1HPGDKMT2AAKR1C2
SCHEMBL1446880 0.84 PLA2G1B (0.33) MEN1HPGDKMT2AALDH1A1RARB
SCHEMBL1447654 0.81 ALDH1A1 (0.36) MEN1KMT2AALDH1A1RARBTSHR
SCHEMBL2852934 0.81 POLB (0.32) LMNAMEN1HPGDKMT2AAKR1C2
SCHEMBL1446637 0.80 ALDH1A1 (0.41) MEN1KMT2AALDH1A1RARBCA1
SCHEMBL722686 0.80 LMNA (0.38) LMNAMEN1HPGDKMT2AAKR1C2
SCHEMBL6904305 0.80 ALDH1A1 (0.34) LMNAMEN1HPGDKMT2AAKR1C2
SCHEMBL8022683 0.79 HDAC3 (0.32) AKR1C2AKR1C1ALOX5PTGESALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
US-20090043050-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2009-02-12 US disclosed
US-7488789-B2 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-02-10 US disclosed
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-18 US disclosed
US-20080306234-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080306219-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080292896-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-11-27 US disclosed
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed
US-6753378-B2 GRAFTED WITH CARBOXYL- OR ANHYDRIDE CONTAINING COMPOUND; MELT PROCESSABILITY, CHEMICAL RESISTANCE, ELECTRICAL AND MECHANICAL PROPERTIES; INJECTION AND BLOW MOLDING; FILMS, SHEETS MITSUI CHEMICALS, INC. (JP) 2004-06-22 US disclosed
US-20030023002-A1 Branched polyolefin, process for producing the same, and thremoplastic resin composition containing branched polyolefin MITSUI CHEMICALS, INC. (JP) 2003-01-30 US disclosed
US-6323150-B1 CONTACTING LIQUID MAGNESIUM COMPOUNDS WITH A LIQUID TITANIUM COMPOUND TO PRECIPITATE A SOLID; REACTING WITH AN ELECTRON DONOR WHICH IS A POLYCARBOXYLIC ESTER OR A COMPOUND HAVING TWO OR MORE ETHER LINKAGES MITSUI CHEMICALS, INC. (JP) 2001-11-27 US disclosed
US-6034189-A COORDINATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST PPIA, PPOX, PTGES2 LMNA 3350/4885MEN1 3097/4885HPGD 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.