Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | GLMN | Q92990 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222459 | 0.90 | KDM4E (0.53) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL1578149 | 0.89 | GRM5 (0.58) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL1579128 | 0.84 | GRM5 (0.54) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL1578956 | 0.84 | GRM5 (0.52) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL1578303 | 0.83 | FAAH (0.62) | KDM4EGRM5RAB9AMAPTAGTR1 | |
| SCHEMBL1578460 | 0.82 | GRM5 (0.54) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL1578601 | 0.81 | GRM5 (0.54) | ALDH1A1KDM4EGRM5P2RX7RAB9A | |
| SCHEMBL1578628 | 0.81 | GRM5 (0.71) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL2280375 | 0.81 | GRM5 (0.52) | ALDH1A1KDM4EGRM5RAB9AMAPT | |
| SCHEMBL2638308 | 0.81 | PABPC1 (0.65) | ALDH1A1KDM4ERAB9AMAPTAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | claimed |
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | disclosed |