Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409891 | 0.79 | PI4KA (0.55) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL24659480 | 0.76 | CYP1A2 (0.39) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL24500614 | 0.75 | KDM4E (0.42) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL23059278 | 0.71 | PDE2A (0.36) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL5011669 | 0.71 | KDM4E (0.59) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL19711588 | 0.70 | ADORA1 (0.35) | ADORA2AADORA1HSD17B10TLR7DYRK1A | |
| SCHEMBL23059275 | 0.70 | ADORA2A (0.33) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL5007676 | 0.70 | XDH (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL23059283 | 0.70 | ADORA2A (0.33) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL23059277 | 0.70 | ADORA2A (0.33) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020250123-A1 | PRMT5 INHIBITORS | LUPIN LIMITED (IN) | 2020-12-17 | — | — | WO | disclosed |