Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130702 | 0.82 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL24659480 | 0.81 | CYP1A2 (0.39) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL10307718 | 0.80 | PDE2A (0.43) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL22787642 | 0.79 | ADORA2A (0.38) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL128577 | 0.79 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL130798 | 0.79 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL130521 | 0.79 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL29685062 | 0.79 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL19117462 | 0.78 | PDE2A (0.42) | PI4KAPI4K2BPI4K2API4KBPDE2A | |
| SCHEMBL31391465 | 0.78 | PDE2A (0.42) | PI4KAPI4K2BPI4K2API4KBPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173609-B2 | Macrolides useful against inflammatory and allergic diseases | BASILEA PHARMACEUTICA AG (CH) | 2012-05-08 | — | — | US | disclosed |
| US-8173609-B2 | Macrolides useful against inflammatory and allergic diseases | BASILEA PHARMACEUTICA AG (CH) | 2012-05-08 | — | — | US | disclosed |