SCHEMBL2278809

SCHEMBL2278809

CCC/C(C)=N\NC(=O)c1ccc2ccccc2c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.67
GAA P10253 2/20 0.67
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
BRCA1 P38398 1/20 0.56
HBB P68871 1/20 0.56
HIF1A Q16665 1/20 0.56
MEN1 O00255 7/20 0.50
KMT2A Q03164 7/20 0.50
KDM4A O75164 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
KDM4E B2RXH2 3/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
LDHA P00338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29586941 1.00 SMN1; SMN2 (0.67) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL6636638 1.00 SMN1; SMN2 (0.67) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL2278812 1.00 SMN1; SMN2 (0.67) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL2276263 0.90 SMN1; SMN2 (0.57) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL2276266 0.90 SMN1; SMN2 (0.57) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL6638592 0.90 SMN1; SMN2 (0.57) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL29607527 0.90 SMN1; SMN2 (0.57) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL2283557 0.86 TP53 (0.61) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL5705734 0.84 SMN1; SMN2 (0.54) SMN1; SMN2GAATP53CYP1A2CYP3A4
SCHEMBL2276912 0.84 SMN1; SMN2 (0.54) SMN1; SMN2GAATP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
US-20230073273-A1 RUBBER COMPOSITION, METHOD FOR PREPARING SAME, AND TIRE FOR CONSTRUCTION VEHICLE THE YOKOHAMA RUBBER CO., LTD. (JP) 2023-03-09 US disclosed
WO-2021132496-A1 RUBBER COMPOSITION, METHOD FOR PREPARING SAME, AND TIRE FOR CONSTRUCTION VEHICLE 横浜ゴム株式会社 2021-07-01 WO disclosed
EP-3725838-A1 RUBBER COMPOSITION FOR TIRE TREAD AND TIRE Bridgestone Corporation (JP) 2020-10-21 EP disclosed
US-20200299490-A1 RUBBER COMPOSITION FOR TIRE TREAD AND TIRE BRIDGESTONE CORPORATION (JP) 2020-09-24 US disclosed
US-10442915-B2 Rubber composition for conveyor belt, and conveyor belt BRIDGESTONE CORPORATION (JP) 2019-10-15 US disclosed
EP-3205692-B1 RUBBER COMPOSITION FOR CONVEYOR BELTS, AND CONVEYOR BELT BRIDGESTONE CORP (JP) 2018-07-18 EP disclosed
US-20170240730-A1 RUBBER COMPOSITION FOR CONVEYOR BELT, AND CONVEYOR BELT BRIDGESTONE CORPORATION (JP) 2017-08-24 US disclosed
EP-3205692-A1 RUBBER COMPOSITION FOR CONVEYOR BELTS, AND CONVEYOR BELT Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2012099955-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2012-07-26 WO disclosed
US-20110196063-A1 RUBBER COMPOSITION FOR TREAD AND TIRE USING THE RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-08-11 US disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 US disclosed
EP-1199331-B1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORP (JP) 2004-03-17 EP disclosed
US-6566449-B2 Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance BRIDGESTONE CORPORATION (JP) 2003-05-20 US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 EP disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed