Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586941 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL2278809 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL2278812 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL2276263 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL2276266 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL6638592 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL29607527 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL2283557 | 0.86 | TP53 (0.61) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL5705734 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2GAATP53CYP1A2CYP3A4 | |
| SCHEMBL2276912 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2GAATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |