SCHEMBL2276263

SCHEMBL2276263

CC/C(C)=N/NC(=O)c1ccc2ccccc2c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
TP53 P04637 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
BRCA1 P38398 1/20 0.57
HBB P68871 1/20 0.57
HIF1A Q16665 1/20 0.57
GAA P10253 2/20 0.53
KMT2A Q03164 8/20 0.51
MEN1 O00255 7/20 0.51
KDM4A O75164 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51
KDM4C Q9H3R0 1/20 0.51
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
LDHA P00338 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2276266 1.00 SMN1; SMN2 (0.57) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL6638592 1.00 SMN1; SMN2 (0.57) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL29607527 1.00 SMN1; SMN2 (0.57) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL29586941 0.90 SMN1; SMN2 (0.67) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL6636638 0.90 SMN1; SMN2 (0.67) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL2278812 0.90 SMN1; SMN2 (0.67) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL2278809 0.90 SMN1; SMN2 (0.67) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL2283557 0.87 TP53 (0.61) SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9
SCHEMBL6636696 0.86 KMT2A (0.60) SMN1; SMN2GAAKMT2AMEN1KDM4E
SCHEMBL1563022 0.86 KMT2A (0.60) SMN1; SMN2GAAKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US claimed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP claimed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO claimed
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP disclosed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO disclosed
US-11760864-B2 Trisulfide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-19 US disclosed
US-11692088-B2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-04 US disclosed
US-20230073273-A1 RUBBER COMPOSITION, METHOD FOR PREPARING SAME, AND TIRE FOR CONSTRUCTION VEHICLE THE YOKOHAMA RUBBER CO., LTD. (JP) 2023-03-09 US disclosed
US-20110196063-A1 RUBBER COMPOSITION FOR TREAD AND TIRE USING THE RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-08-11 US disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 US disclosed
EP-1199331-B1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORP (JP) 2004-03-17 EP disclosed
US-6566449-B2 Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance BRIDGESTONE CORPORATION (JP) 2003-05-20 US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 EP disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760864-B2 Trisulfide compound TST, TMT1A, SULT1A1 SMN1; SMN2 2843/4885TP53 2514/4885CYP1A2 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.