SCHEMBL2283557

SCHEMBL2283557

CC(C)=NNC(=O)c1ccc2ccccc2c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
BRCA1 P38398 1/20 0.61
HBB P68871 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HIF1A Q16665 1/20 0.61
KMT2A Q03164 8/20 0.55
MEN1 O00255 7/20 0.55
KDM4A O75164 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
KDM4C Q9H3R0 1/20 0.55
LDHA P00338 1/20 0.54
KDM4E B2RXH2 2/20 0.54
MAPT P10636 2/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6638592 0.87 SMN1; SMN2 (0.57) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2276266 0.87 SMN1; SMN2 (0.57) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2276263 0.87 SMN1; SMN2 (0.57) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL29607527 0.87 SMN1; SMN2 (0.57) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2278809 0.86 SMN1; SMN2 (0.67) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2278812 0.86 SMN1; SMN2 (0.67) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL29586941 0.86 SMN1; SMN2 (0.67) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL6636638 0.86 SMN1; SMN2 (0.67) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5705734 0.84 SMN1; SMN2 (0.54) TP53CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2276914 0.84 SMN1; SMN2 (0.54) TP53CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US claimed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP claimed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO claimed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 EP claimed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US claimed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP claimed
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP disclosed
CN-114521202-B Rubber composition, method for producing same, and tire for engineering vehicle 横滨橡胶株式会社 2024-01-26 CN disclosed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO disclosed
US-11760864-B2 Trisulfide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-19 US disclosed
US-6566449-B2 Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance BRIDGESTONE CORPORATION (JP) 2003-05-20 US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 US disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 EP disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760864-B2 Trisulfide compound TST, TMT1A, SULT1A1 TP53 2514/4885CYP1A2 1130/4885CYP3A4 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.