Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24160595 | 0.86 | KDM4E (0.34) | KDM4EGAACA12CA2POLB | |
| SCHEMBL22521042 | 0.85 | VHL (0.32) | KDM4EGAA | |
| SCHEMBL24159937 | 0.85 | ALDH1A1 (0.32) | KDM4EGAAALOX15MALT1 | |
| SCHEMBL23739482 | 0.85 | MTNR1A (0.34) | KDM4EGAAALOX15 | |
| SCHEMBL24159953 | 0.84 | KDM4E (0.31) | KDM4EGAAALOX15THRB | |
| SCHEMBL22789129 | 0.83 | KDM4E (0.32) | KDM4EGAAPOLBALOX15THRB | |
| SCHEMBL22789062 | 0.83 | CDC25B (0.33) | KDM4EGAAPOLBALOX15THRB | |
| SCHEMBL23739531 | 0.83 | MTNR1A (0.39) | NAMPT | |
| SCHEMBL23298785 | 0.83 | CDC25B (0.38) | KDM4EGAAPOLBALOX15MEN1 | |
| SCHEMBL24160586 | 0.82 | KDM4E (0.31) | KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | disclosed |
| WO-2020249048-A1 | ALK PROTEIN REGULATOR AND ANTI-TUMOR APPLICATION THEREOF | 上海科技大学 | 2020-12-17 | — | — | WO | disclosed |