Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790158 | 0.73 | KHK (0.46) | LMNANR1H4MEN1KMT2AGPBAR1 | |
| SCHEMBL22790286 | 0.71 | NR1H4 (0.40) | LMNANR1H4MEN1KMT2AGPBAR1 | |
| SCHEMBL22790343 | 0.69 | KHK (0.46) | — | |
| SCHEMBL7647236 | 0.68 | ADRB1 (0.52) | KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10254311 | 0.68 | KMT2A (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28539878 | 0.68 | HTR2A (0.31) | — | |
| SCHEMBL22790093 | 0.68 | NR4A2 (0.52) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7940843 | 0.67 | HTR2B (0.36) | MEN1KMT2A | |
| SCHEMBL2433825 | 0.67 | KMT2A (0.48) | LMNAMEN1KMT2ACNR2ALDH1A1 | |
| SCHEMBL1096533 | 0.67 | CDK2 (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |