Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27640907 | 0.79 | KDM4E (0.37) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL22789981 | 0.74 | NR4A2 (0.49) | NR1H4MEN1KMT2ALMNA | |
| SCHEMBL22790158 | 0.74 | KHK (0.46) | NR1H4MEN1KMT2AGPBAR1LMNA | |
| SCHEMBL10254311 | 0.72 | KMT2A (0.49) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL22790182 | 0.71 | LMNA (0.38) | NR1H4MEN1KMT2AGPBAR1LMNA | |
| SCHEMBL22789953 | 0.71 | NR4A2 (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL22790088 | 0.71 | NR4A2 (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL22789951 | 0.71 | NR4A2 (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL15167291 | 0.70 | ACMSD (0.44) | NR1H4MEN1KMT2AGPBAR1LMNA | |
| SCHEMBL2433825 | 0.70 | KMT2A (0.48) | MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |