Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4487460 | 0.84 | ADRB1 (0.50) | ADRB1MAPTHTR2BHTR2AHTR2C | |
| SCHEMBL7943366 | 0.84 | MAPT (0.38) | ADRB1MAPTHTR2BHTR2AHTR2C | |
| SCHEMBL7940843 | 0.84 | HTR2B (0.36) | ADRB1HTR2BHTR2AHTR2CHTR7 | |
| SCHEMBL746788 | 0.84 | ADRB1 (0.47) | ADRB1HTR2BHTR2AHTR2CMAPK1 | |
| Hydrochloric Acid SCHEMBL6374876 | 0.83 | ADRB1 (0.49) | ADRB1MAPTHTR2BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6830556 | 0.82 | ADRB1 (0.46) | ADRB1HTR2BHTR2AHTR2CMAPK1 | |
| SCHEMBL3017728 | 0.81 | ADRB1 (0.56) | ADRB1MAPTHTR2BHTR2AHTR2C | |
| SCHEMBL22914744 | 0.81 | POLB (0.46) | HTR2BHTR2AHTR2CPOLBELANE | |
| SCHEMBL19003593 | 0.81 | MGLL (0.39) | ADRB1MAPTHTR2BHTR2AHTR2C | |
| SCHEMBL38662505 | 0.81 | ADRB2 (0.50) | HTR2BHTR2AHTR2CALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226159-A1 | SUBSTITUTED DIPEPTIDES HAVING NOS INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032690-A1 | SUBSTITUTED DIPEPTIDES HAVING NOS INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-10 | — | — | WO | disclosed |