Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029692 | 0.85 | MGLL (0.44) | MGLLSMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL22856428 | 0.82 | MGLL (0.32) | MGLLCHRM2CHRM3 | |
| SCHEMBL23568918 | 0.82 | MGLL (0.49) | MGLLSMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL25829095 | 0.72 | MGLL (0.45) | MGLLCHRM3 | |
| SCHEMBL22856550 | 0.72 | MGLL (0.47) | MGLLCHRM2CHRM3 | |
| SCHEMBL25887901 | 0.72 | L3MBTL1 (0.47) | MGLL | |
| SCHEMBL23806770 | 0.71 | MGLL (0.47) | MGLLCHRM2CHRM3 | |
| SCHEMBL22297419 | 0.70 | MGLL (0.36) | MGLL | |
| SCHEMBL18478531 | 0.69 | SMN1; SMN2 (0.48) | MGLLSMN1; SMN2CHRM2CHRM3EPHX2 | |
| SCHEMBL18478131 | 0.69 | SMN1; SMN2 (0.43) | MGLLSMN1; SMN2CHRM2CHRM3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251972-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |