Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776589 | 0.91 | PTGER4 (0.41) | PTGER4L3MBTL1LDHALDHBALOX5AP | |
| SCHEMBL22791384 | 0.89 | PTGER4 (0.38) | PTGER4KDM4EALDH1A1SMN1; SMN2RPS6KB1 | |
| SCHEMBL22776720 | 0.88 | PTGER4 (0.37) | PTGER4L3MBTL1KDM4EPDE9ARORC | |
| SCHEMBL22791390 | 0.85 | KDM4E (0.35) | PTGER4L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22776650 | 0.81 | PTGER4 (0.53) | PTGER4RORC | |
| SCHEMBL22776648 | 0.81 | PTGER4 (0.53) | PTGER4RORC | |
| SCHEMBL29614504 | 0.81 | PTGER4 (0.53) | PTGER4RORC | |
| SCHEMBL29614485 | 0.79 | PTGER4 (0.44) | PTGER4RORC | |
| SCHEMBL22776540 | 0.79 | PTGER4 (0.42) | PTGER4KDM4EALDH1A1LDHALDHB | |
| SCHEMBL29614541 | 0.78 | PTGER4 (0.51) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |