Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776609 | 0.90 | LDHA (0.39) | L3MBTL1LDHALDHBTRPV1SRD5A2 | |
| SCHEMBL29527167 | 0.90 | LDHA (0.39) | L3MBTL1LDHALDHBTRPV1SRD5A2 | |
| SCHEMBL22776473 | 0.88 | KDM4E (0.36) | KDM4EL3MBTL1LDHALDHBTRPV1 | |
| SCHEMBL22791244 | 0.85 | PTGER4 (0.36) | KDM4EALDH1A1SMN1; SMN2SCN9AL3MBTL1 | |
| SCHEMBL22791384 | 0.84 | PTGER4 (0.38) | KDM4EALDH1A1SMN1; SMN2SCN9AJAK2 | |
| SCHEMBL22777142 | 0.80 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL22777144 | 0.80 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL29614449 | 0.80 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL22791199 | 0.79 | HTR4 (0.44) | — | |
| SCHEMBL22791393 | 0.78 | PDE2A (0.35) | SCN9AL3MBTL1LDHALDHBNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |