Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12105119 | 0.89 | DAO (0.39) | BRD4CREBBPTLR8TLR7DAO | |
| SCHEMBL16555972 | 0.77 | ALDH1A1 (0.45) | TLR8TLR7DAOFDPSL3MBTL1 | |
| SCHEMBL7100687 | 0.77 | DAO (0.43) | BRD4TLR8TLR7DAOFDPS | |
| SCHEMBL24671995 | 0.77 | TP53 (0.43) | DAOFDPSCA12CA1CA2 | |
| SCHEMBL28186255 | 0.76 | FDPS (0.40) | DAOFDPSCA12CA1CA2 | |
| SCHEMBL796651 | 0.76 | — | — | |
| SCHEMBL45207 | 0.74 | TLR8 (0.44) | TLR8TLR7DAOFDPSL3MBTL1 | |
| Bromide SCHEMBL556174 | 0.74 | TLR8 (0.44) | TLR8TLR7DAOFDPSL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6736377 | 0.74 | TLR8 (0.44) | TLR8TLR7DAOFDPSL3MBTL1 | |
| Hydrochloric Acid SCHEMBL557786 | 0.74 | TLR8 (0.44) | TLR8TLR7DAOFDPSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985005-A1 | FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR | Medshine Discovery Inc. (CN) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020249096-A1 | FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR | 南京明德新药研发有限公司 | 2020-12-17 | — | — | WO | disclosed |