Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792313 | 0.89 | L3MBTL1 (0.50) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792331 | 0.85 | CYP1A2 (0.50) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792619 | 0.79 | ALDH1A1 (0.52) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL1678795 | 0.79 | LTA4H (0.53) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792060 | 0.79 | LTA4H (0.53) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792284 | 0.79 | LTA4H (0.53) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL13101037 | 0.79 | MEN1 (0.58) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792616 | 0.78 | MEN1 (0.51) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792621 | 0.78 | CYP1A2 (0.54) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22792288 | 0.78 | ALDH1A1 (0.51) | POLBL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |