⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792895 | 0.59 | — | — | |
| SCHEMBL22792661 | 0.59 | — | — | |
| SCHEMBL22793177 | 0.46 | — | — | |
| SCHEMBL8215570 | 0.41 | — | — | |
| SCHEMBL50659 | 0.40 | ALDH1A1 (0.38) | — | |
| SCHEMBL424728 | 0.39 | TSHR (0.73) | — | |
| SCHEMBL93161 | 0.39 | GABRA1 (0.69) | — | |
| SCHEMBL7132801 | 0.39 | ALDH1A1 (0.53) | — | |
| SCHEMBL9537161 | 0.38 | — | — | |
| SCHEMBL10287789 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015566-A | Stabilizer composition, use of a stabilizer composition, method for stabilizing polycondensates against hydrolytic degradation, and hydrolytically stable compositions and mouldings or mouldings thereof | 弗劳恩霍夫应用研究促进协会 | 2023-11-07 | — | — | CN | disclosed |
| US-10988466-B2 | Heterocyclic derivatives useful as SHP2 inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| US-20200392128-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2020-12-17 | — | — | US | disclosed |