SCHEMBL2279406

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2276431	0.89	ADRA2C (0.41)	HTR2CDRD2MAPTNPC1ALDH1A1
	SCHEMBL27830463	0.89	HTR2C (0.45)	HTR2CDRD2MAPTNPC1VNN1
	SCHEMBL13466298	0.85	EGFR (0.39)	HTR2CDRD2MAPTNPC1ALDH1A1
	SCHEMBL2280749	0.81	VNN1 (0.43)	HTR2CDRD2MAPTNPC1ALDH1A1
	SCHEMBL12374014	0.81	F10 (0.39)	DRD2MAPTNPC1ALDH1A1RAB9A
	SCHEMBL27848858	0.80	HTR2C (0.48)	HTR2C
	SCHEMBL12373988	0.78	AGXT (0.40)	DRD2MAPTNPC1ALDH1A1RAB9A
	SCHEMBL12310384	0.78	DRD2 (0.44)	HTR2CDRD2MAPTNPC1ALDH1A1
	SCHEMBL12373931	0.78	HTR2C (0.40)	HTR2CMAPTCACNA2D1MEN1GFER
	SCHEMBL2277665	0.77	S1PR1 (0.42)	HTR2CNUAK1EGFRNUAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.