Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 10/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24514534 | 0.89 | EIF2AK4 (0.34) | SORDEIF2AK4CDK9IDH1CCNT1 | |
| SCHEMBL25468524 | 0.80 | GRM1 (0.33) | SORDEIF2AK4CDK9CCNT1 | |
| SCHEMBL25110569 | 0.78 | SORD (0.31) | SORD | |
| SCHEMBL25110555 | 0.78 | GRM1 (0.32) | EIF2AK4 | |
| SCHEMBL25109033 | 0.77 | SORD (0.30) | SORD | |
| SCHEMBL25109036 | 0.76 | FGFR1 (0.31) | OPRM1 | |
| SCHEMBL25109488 | 0.76 | FGFR1 (0.31) | OPRM1 | |
| SCHEMBL25482380 | 0.74 | SORD (0.38) | SORDJAK2JAK1TYK2OPRM1 | |
| SCHEMBL16803140 | 0.73 | LMNA (0.37) | CDK9CCNT1 | |
| SCHEMBL25125425 | 0.67 | OPRM1 (0.38) | SORDJAK2JAK1TYK2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251971-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |